Continuous Versus Discontinuous Design of Encircling Lesions During Ablation for Atrial Fibrillation

Acute Efficacy of Point-by-point Radiofrequency Ablation for Pulmonary Vein Isolation in Patients With Atrial Fibrillation: a Randomized Comparison of Continuous Versus Discontinuous Design of Encircling Lesions

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03332862

Acronym

CDAF

Enrollment

Registered

2017-11-06

Start date

2017-09-15

Completion date

2018-01-31

Last updated

2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

Catheter Ablation, Atrial Fibrillation, Contact Force, Continuous Ablation

Brief summary

Acute efficacy of point-by-point radiofrequency ablation for pulmonary vein isolation in patients with atrial fibrillation are comparable independantly of the ablation strategy (continous versus discontinuous ablation) under the same condition of power delivery.

Detailed description

The number of pulmonary vein isolation (PVI) therapy for atrial fibrillation (AF) is increasing. Durable PVI is cornerstone for long-term freedom of AF. In one previous study continuous ablation was suggested to be more efficient in durable PVI. However, this hypothesis has not been proven in randomized fashion. The current study is to confirm whether continuous versus discontinuous design of encircling lesions are comparable under the same conditions of power delivery. The study design is a two-centre prospective randomized trial to compare the acute efficacy by using the above described approaches.

Interventions

PROCEDUREcatheter ablation

catheter ablation for atrial fibrillation treatment

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients undergoing pulmonary vein isolation with radiofrequency catheter ablation for paroxysmal atrial fibrillation treatment.

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Combined unsuccessful PVI or PV reconnection	30 min after ablation	Combined unsuccessfuk PVI after completeing the primary lesion set or PV reconnection during the waiting time

Secondary

Measure	Time frame	Description
Early pulmunary veins reconnection	10 min.	Early pulmunary veins reconnection within the first 10 min after PVI

Countries

Czechia

Contacts

Primary ContactBashar Aldhoon, MD, PhD

baaĺ@ikem.cz+420739528025

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026