Effect of Intake of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Blood Cholesterol.

A 12-week, Randomized, Double-blind, Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Improvement of Blood Cholesterol

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03332641

Enrollment

Registered

2017-11-06

Start date

2017-06-07

Completion date

2017-09-28

Last updated

2017-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidemia

Brief summary

This study was conducted to investigate the effects of daily supplementation of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on improvement of Blood Cholesterol.

Detailed description

This study was a 12 weeks, randomized, double-blind, placebo-controlled human trial. Twenty subjects were randomly divided into Citron(Citrus Junos Siebold ex Tanaka) Peel Extract or a placebo group. Blood cholesterol profiles before and after the intervention.

Interventions

DIETARY_SUPPLEMENTCitron peel extract

Citron peel extract for 12 weeks

DIETARY_SUPPLEMENTPlacebo

Placebo for 12 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

19 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* Age 19-75 years with Total cholesterol 200-239 mg/dL

Exclusion criteria

* Lipid lowering agent within past 6 months * Severe cardiovascular disease(Mvodardial infarction, stroke, etc) * Renal disease(Heredity hyperlipidemia, Acute/Chronic renal failure, Nephrotic syndrome, ect) * Cancer, Respiratory organ disease(Asthma, Chronic obstructive pulmonary disease) * Diabetes mellitus * Allergic or hypersensitive to any of the ingredients in the test products * History of disease that could interfere with the test products or impede their absorption * Under antipsychotic drugs therapy within past 2 months * History of alcohol or substance abuse * Participation in any other clinical trials within past 2 months * Laboratory test by show the following results * Pregnancy or breast feeding * Not Contraception(except: Surgery for female infertility)

Design outcomes

Primary

Measure	Time frame	Description
Changes of Cholesterol	12 weeks	Changes of Cholesterol were assessed before and after the intervention

Secondary

Measure	Time frame	Description
Changes of Lipid profile	12 weeks	Changes of Lipid profile were assessed before and after the intervention
Changes of Oxidized LDL	12 weeks	Changes of Oxidized LDL were assessed before and after the intervention

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026