Malnutrition, Surgery
Conditions
Brief summary
Randomized intervention by nutritional supplements and training in postoperative patients after discharge
Detailed description
Surgery combined with malnutrition is associated with loss of muscle mass and leads to serious consequences for the surgical patient. A majority of surgical patients continue to lose weight after discharge. Nutritional risk screening has not been fully implemented at Landssjúkrahúsið - the National Hospital of the Faroe Islands and therefore the prevalence of patients at nutritional risk is unknown. The aim of this study is to examine whether an intervention with independent nutritional supplements or an intervention combining nutritional supplements and resistance training is more effective in preventing loss of muscle mass than standard care in surgical patients following discharge. Secondary outcomes are changes in body weight, quality of life, muscle strength and activities of daily living. Furthermore, we want to screen hospitalized surgical patients for nutritional risk in order to get an estimate of the prevalence of nutritional risk.
Interventions
DIETARY_SUPPLEMENTNutrition
150 Faroese surgical patients randomized to one of the following three arms 1) oral nutritional supplements and advice, 2) oral nutritional supplements and training exercise and 3) Standard hospital procedure. Primary outcome is loss of lean body mass
Sponsors
Health Insurance Fund of Research Council Faroe Islands
National Hospital of the Faroe Islands
Société des Produits Nestlé (SPN)
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
Baseline data are collected prior to the randomization and thus are masked. But during and after the intervention both participants and investigators are unblinded.
Intervention model description
3 groups of 50 patients each by randomization
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Admitted to the surgical departments at Landssjúkrahúsið - National Hospital of Faroe Islands * Aged 18 years or above * One or more of the following surgical procedures: knee alloplasty, hip alloplasty, collum femoris fracture, back fracture, abdominal surgery, mamma surgery and other comprehensive surgery * At nutritional risk according to screening
Exclusion criteria
* Minimally invasive surgery/Laparoscopic surgery * Severely reduced kidney function (p-creatinin\>250 mikromol/l) or dialysis * Terminal illness * Inability to cooperate in tests or exercises due to cognitive function or dementia * Admitted to intensive care unit * Inability to speak or understand Faroese, Danish or English * Consent according to national regulations not obtainable
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Loss of lean body mass | 8 weeks | Non-bone lean mass measured by dual energy x-ray absorptiometry (DXA) whole-body scans |
Countries
Faroe Islands
Outcome results
None listed