Tomography, Optical Coherence, Retina
Conditions
Brief summary
Improvement of retinal medical imaging opens new perspectives for exploring the retinal structures. Optical coherence spectral domain (SD-OCT), which has been widely used in the last ten years, is certainly the most advanced device. In the analysis of patients without retinal disease using SD-OCT, granulations in the interdigitation area were observed. These granulations have never been described with this device. They could correspond either to the degradation products of the external segments of the photoreceptors or to melanosomes. A descriptive study of these granulations at different examination times and in different lighting situations would allow us to obtain essential information for a better understanding of this area. Based on the results, larger studies could explore this area more finely in retinal pathologies involving dysfunctions of photoreceptors or of the pigmentary epithelium.
Interventions
Five SD-OCTs will be performed with various conditions of enlightenment.
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patient aged 18 years or older * Consent to participate
Exclusion criteria
* Retinal abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variation of the number of hyperreflective granulations in the interdigitation area according to time and enlightenment | 1 hour after baseline |
Countries
France
Outcome results
None listed