Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction

Comparative Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03326570

Enrollment

110

Registered

2017-10-31

Start date

2011-08-25

Completion date

2019-04-01

Last updated

2019-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Keywords

Lung cancer, Data collection post bronchoscopy

Brief summary

The goal of this clinical research study is learn about side effects and the success of bronchoscopies when performed in cancer patients with and without symptoms. This is an investigational study. Up to 110 patients will take part in this study. All will be enrolled at MD Anderson.

Detailed description

If participant agrees to take part in this study, researchers will collect information from participant's medical records. Length of Study: Researchers will continue to collect participant's medical information for up to 2 years. Additional Information: Participant's data will be kept in a database on a password-protected computer in a secure office. This information will only be available to the study doctors and staff.

Interventions

BEHAVIORALMedical Data Collection

Medical information collected after bronchoscopy for up to 2 years.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

° All patients undergoing interventional bronchoscopy during the first 12 months will be enrolled, with follow-up occurring out to 2 years from the study startup (the duration of the grant).

Exclusion criteria

* Age less than 18 years, * Inability to participate in telephone follow-up

Design outcomes

Primary

Measure	Time frame	Description
Time to Any Complication Requiring Treatment	2 years	Researchers will estimate the hazard function of time to any complications in the framework of competing risks while death is the competing risk.3 Researchers will graphically visualize the hazard function of time to any complications using Kernel smoothing method.

Secondary

Measure	Time frame	Description
Quality-Adjusted Survival	2 years	Researchers will evaluate the relationship between covariates and quality-adjusted survival.

Other

Measure	Time frame	Description
Early Intervention	2 years	Early intervention cases defined as those with anatomic narrowing and no or mild dyspnea (as measured by the Borg score).
Late Intervention	2 years	Late intervention cases defined as those with moderate or severe dyspnea due to airway narrowing.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026