Sleeve Gastrectomy
Conditions
Keywords
Obesity, bariatric surgery, sleeve gastrectomy, physical activity, movement analysis
Brief summary
This study aims to describe the effects of sleeve gastrectomy, the most commonly performed bariatric procedure worldwide, on functional capacity, habitual physical activity, physical fitness (cardiorespiratory and muscular fitness) and gait parameters in severely obese subjects undergoing bariatric surgery. Functional capacity, physical activity, physical fitness and gait parameters will be objectively assessed and compared among candidates seeking sleeve gastrectomy and 6 months after sleeve gastrectomy.
Detailed description
This study is a monocentric longitudinal study conducting in obese patients: candidates to sleeve gastrectomy and these same patients 6 months after.The primary aim of this study is to describe the effects of sleeve gastrectomy on habitual physical activity, physical fitness (cardiorespiratory and muscular fitness) and gait parameters in severely obese patients. Functional capacity will be assessed during a 6-min walk test, habitual physical activity with accelerometers during 7-day recordings in habitual life conditions (Actigraph GT3X® and activPAL®), cardiorespiratory fitness during a maximal exercise test on a cycle ergometer with a direct measure of peakVO2, muscle strength with an isokinetic dynamometer (Contrex®), muscle power and postural stability with force platforms (Kistler® and Satel®) and gait parameters with a gait analysis system (GaitRite®). Fatigue, quality of life and joint pain will be assessed with questionnaires (MFI-20, SF36 and WOMAC, respectively).
Interventions
assessment of functional capacity, habitual physical, cardiorespiratory fitness, muscle power and postural stability and gait parameters
Sponsors
Assistance Publique - Hôpitaux de Paris
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Intervention model description
Longitudinal study comparing data before bariatric surgery and one year after bariatric surgery
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Female gender * Age between 18 and 65 years * Planned obesity treatment by sleeve gastrectomy * Patient with massive obesity (BMI ≥ 40 kg/m2) or severe obesity (BMI between 35 and 40 kg/m2) with comorbidities * Written informed consent
Exclusion criteria
* Subject not affiliated with a social security scheme * Regular follow-up not feasible * Participation in a structured physical activity program * Severe orthopedic problems * Disabling neuropathy * Recent (\< 6 months) coronary event * Abnormal cardiac stress test * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| functional capacity | before and 6 months after sleeve gastrectomy | Difference in functional capacity (6-min walk test distance) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| habitual physical activity (Actigraph GT3X® and activPAL®) | before and 6 months after sleeve gastrectomy | Difference in habitual physical activity |
| cardiorespiratory fitness ( cycle ergometer ) | before and 6 months after sleeve gastrectomy | Difference in cardiorespiratory fitness |
| muscle strength ( isokinetic dynamometer (Contrex®)) | before and 6 months after sleeve gastrectomy | Difference in muscle strength |
Countries
France
Outcome results
None listed