The Comparison About the Response of Ursodeoxycholic Acid in Primary Biliary Cholangitis Only and Primary Biliary Cholangitis With High Immune Globulin G or Aminotransferase at West China Hospital

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03322943

Enrollment

300

Registered

2017-10-26

Start date

2016-01-01

Completion date

2018-12-30

Last updated

2019-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Biliary Cholangitis

Keywords

Ursodeoxycholic Acid, Response

Brief summary

This study evaluates the different response of Ursodeoxycholic Acid in primary biliary cholangitis only and primary biliary cholangitis with high immune globulin G or aminotransferase at West China Hospital from 2008-2017.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

25 Years to 85 Years

Healthy volunteers

Inclusion criteria

Patients diagnosed with primary biliary cholangitis Treated with Ursodeoxycholic Acid in West China Hospital for at least 1 year

Exclusion criteria

Autoimmune hepatitis Primary sclerosing cholangitis

Design outcomes

Primary

Measure	Time frame	Description
Description of demographics, clinical index after treatment	up to 1 year	age，sex，ALT（IU/L），AST（IU/L），ALP（IU/L），GGT（IU/L）,IgG（g/L）

Secondary

Measure	Time frame	Description
Evaluation whether the PBC patients have response after treatment	within 1 year	Use Paris II criterion to estimate

Countries

China

Outcome results