Legionnaires' Disease
Conditions
Brief summary
The goal of this study is to determine whether survivors of Legionnaires' disease suffer smell loss. A quantitative olfactory test will be performed by the participants. Such testing will require approximately 20-30 minutes of the participant's time. The participants will take the University of Pennsylvania Smell Identification Test (UPSIT), a scratch-and-sniff test to assess their ability to identify odors in a forced- choice format. Volunteers will also complete a questionnaire asking personal history, demographic questions, and medical history.
Interventions
OTHERThe University of Pennsylvania Smell Identification Test (UPSIT)
This standardized test, the most widely used olfactory test in the world, is derived from basic psychological test measurement theory and focuses on the comparative ability of subjects to identify odorants at the suprathreshold level. The UPSIT consists of four envelope-sized booklets, each containing ten scratch and sniff odorants embedded in 10- 50-µm polymer microcapsules positioned on brown strips at the bottom of the pages of the booklets.
Sponsors
University of Pennsylvania
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Persons of generally good health, as obtained from a screening questionnaire who are 18 years of age and older * Both men and women of all ethnic backgrounds will be accepted.
Exclusion criteria
* Age less than 18 * Pregnant Women * Persons who mental competence is limited, such as those with dementia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Score on the University of Pennsylvania Smell Identification Test | 20-30 Minutes | The number of correct odor identification responses out of 40 from the standardized University of Pennsylvania Smell Identification Test. The total number of correct responses will then be compared to standard norms of correct responses based on demographic information such as age and sex. Comparing the scores to the standard norms collected will indicate whether a volunteer is normosmic, hyposmic, or anosmic. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Questionnaire Responses | 20-30 Minutes | These are various demographic and medical history questions regarding exposure to Legionella Pneumonia and current experiences post diagnosis and treatment. |
Countries
United States
Outcome results
None listed