Mucosal Melanoma
Conditions
Brief summary
Primary mucosal melanomas (MPM) are rarer than cutaneous melanomas, but also more severe. They are usually refractory to conventional approaches, regularly excluded from major therapeutic programs and not sensitive to new targeted therapies orphans. The identification of therapeutic targets and accessibility to existing, developing or future targeted therapies improves the survival of patients with MPM. The principal goal is to describe, using a large panel of genes, the prevalence of major mutations in a cohort of MPMs based on the population of a French region.
Interventions
GENETICSomatic Genetic
NGS analysis
Sponsors
CHU de Reims
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Incident Mucosal melanoma in the Champagne-Ardenne region 2004-2014
Exclusion criteria
* Cutaneous melanoma * Uveal melanoma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The frequency of main mutations identified using the NGS panel | Day 0 | NGS panel |
Countries
France
Outcome results
None listed