Chronic Pain Syndrome
Conditions
Brief summary
To evaluate and compare the NoL index variations after a painful physiotherapy exercise in patients with upper limb CRPS, before and after a stellate ganglion block.
Interventions
DEVICENoL index
The NoL/PMD-200 (Medasense Biometrics Ltd, Ramat Yishai, Israel) is a multi-parameter index (0-100) that incorporates heart rate, heart rate variability (0.15-0.4 Hz band power), plethysmograph wave amplitude, skin conductance level, number of skin conductance fluctuations (NSCF), and their time derivatives9 using a non-linear regression technique. A higher index indicates higher nociception, and an index \<20 indicates adequate analgesia.
Sponsors
Maisonneuve-Rosemont Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of upper limb CRPS according to the Budapest criteria12, for more than 6 months; * Significant pain relief from stellate ganglion block; * Undergoing physical therapy; * 18 years and older.
Exclusion criteria
* Patients taking beta blockers * Bilateral/generalized CRPS * Patients needing sedation for the procedure * Inability to understand a Numeric Pain rating Scale due to cognitive dysfunction or linguistic barrier * Movement disorder making a person unable to lie still for the duration of the evaluation period. * Patient refusal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in NoL index from baseline | 20 minutes | • Change in the NoL index after a painful physiotherapy exercise in patients with upper limb CRPS 20 minutes after a stellate ganglion block, from baseline (before the stellate ganglion block) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in peak NoL index values before and after a stellate ganglion block | 20 minutes | Measure the change in peak NoL index (peak NoL index after a painful physiotherapy exercise before the stellate ganglion block minus the peak NoL index value after a painful physiotherapy exercise after the stellate ganglion block |
| change in Numeric Rating Scale (NRS) pain intensity score (from 0-10) before and after a stellate ganglion block | 20 minutes | Measure the change in NRS pain intensity score after a painful physiotherapy exercise, before and 20 minutes after a stellate ganglion block. |
| correlation between change in NoL index and change in the Numeric Rating Scale (NRS) pain score (from 0-10) from baseline | 20 minutes | Correlate the NoL index variation (delta NoL) with the NRS pain score variation (delta NRS) painful physiotherapy exercise in patients with upper limb CRPS, before and 20 minutes after a stellate ganglion block. |
Countries
Canada
Outcome results
None listed