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Podocyturia as Predictive Factor for Pre-eclampsia

Prospective Study : Podocyturia as Predictive Factor for Pre-eclampsia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03316430
Acronym
PEPOD1
Enrollment
1000
Registered
2017-10-20
Start date
2019-05-15
Completion date
2021-12-07
Last updated
2022-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-Eclampsia

Brief summary

Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity. Podocyn could be identified in the urine, before proteinuria, a key element in the diagnostic of pre-eclampsia. Preventive treatment using aspirin could be administrated in early pregnancy. We hypothesized that podocyturia could be an early indicator of preeclampsia. This is a prospective, non-interventional, monocentric study.

Interventions

OTHERPodocyturia quantification

Podocyturia quantification at first planned prenatal care visit before 16 weeks of gestation

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* women aged 18 years or more * single pregnancy * first planned prenatal visit before 16 weeks of gestation * planned delivery at Hôpital Femme Mère Enfant in Lyon, France * patient receiving information and non opposition to participate

Exclusion criteria

* multiple pregnancy * pregnancy stopped * antecedent of nephropathy * inability to understand information provided * prisoner or under administrative supervision * fetal malformation, chromosomal anomalies * preterm delivery for other reason that any hypertensive disorder of pregnancy or Intrauterine growth restriction

Design outcomes

Primary

MeasureTime frameDescription
Occurrence of pre-eclampsiaAt childbirth (around 8 months)Occurrence of pre-eclampsia during pregnancy

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026