Lymph Node Metastases and Arterial Ligation in Rectal Cancer Surgery

Localisation of Mesenteric Lymph Node Metastases and Role of Level of Arterial Ligation in Rectal Cancer Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03314961

Enrollment

151

Registered

2017-10-19

Start date

2012-01-31

Completion date

2016-12-31

Last updated

2017-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymph Node Metastases

Keywords

rectal cancer

Brief summary

Lymph node status is of major prognostic importance in non-metastatic rectal cancer. For oncological reasons, central arterial ligation of the inferior mesenteric artery (IMA) is suggested. However, there is no conclusive evidence presented for this procedure. This study aimed at investigating the localisation of lymph node metastases and the role of central versus peripheral arterial ligation of in rectal cancer specimens.

Detailed description

Prospective population-based study of specimens from patients that underwent surgical resection for rectal cancer in Västmanland County, Sweden. Specimens were divided in 3 sections (A-C) and the total amount of lymph nodes and the location of lymph node metastases were analysed. Multivariate analysis was used to explore the relationship between lymph node counts and age, gender, BMI, preoperative oncological treatment, type of surgery, tumour stage, vessel and specimen length.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* All patients that were curatively operated for rectal cancer in Västmanlands county 2012-2016.

Exclusion criteria

* Patients that were not operated or had another type of cancer.

Design outcomes

Primary

Measure	Time frame	Description
Lymph node metastases in rectal cancer	2012-2016	Analyses of number and location of lymph node metastases in rectal cancer

Outcome results