Study of the Diaphragmatic Function by Transient Elastography (ELASTODIAPH)

Study of the Diaphragmatic Function by Transient Elastography : Comparison With Mechanical and Electrophysiological Variables

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03313141

Acronym

ELASTODIAPH

Enrollment

Registered

2017-10-18

Start date

2017-10-09

Completion date

2017-10-27

Last updated

2017-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

The study of diaphragmatic function is usually measured by the pressures and volumes generated by contraction of the diaphragm, which is often difficult (cumbersome technique, difficulty to obtain a perfect cooperation of the subjects, and difficulty to specifically analyze the diaphragm compared to other accessory respiratory muscle groups). In this study, the investigators aimed at analysing diaphragmatic function by measuring the shortening, stiffness, strain and thickening of the diaphragm by ultrasound.

Interventions

DIAGNOSTIC_TESTUltrasound

Volitional and non volitional respiratory tasks

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Intervention model description

To compare diaphragm elastrography provided by ultrasound to diaphragm function indices provided by magnetic/electrical phrenic nerves stimulation

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy volunteer

Exclusion criteria

* chronic respiratory, neurologic or cardiac disease * swallowing disorders * pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Transdiaphragmatic pressure	2 hours	The transdiaphragmatic pressure is the sum of absolute values of gastric and oesophagal pressures

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026