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Investigating Memory Retrieval Improvement in Healthy Subjects

Investigating Memory Retrieval Improvement in Healthy Subjects

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03312920
Enrollment
0
Registered
2017-10-18
Start date
2017-09-27
Completion date
2024-09-05
Last updated
2025-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Adults

Keywords

tDCS, accelerated learning, memory

Brief summary

The purpose of this study is to investigate whether learning can be accelerated and associative memory performance improved in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.

Detailed description

Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory. Transcranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether learning can be accelerated and associative memory improved by using tDCS, this study will compare the performance in a Face Name Associate memory task from 3 groups. The first group will get active aodal tDCS during the study phase of the Face Name Memory task, whereas the second group will get sham tDCS during the study phase of the task and the third group will get active cathodal tDCS.

Interventions

active anodal tDCS with memory task

DEVICEsham tDCS

sham tDCS with memory task

DEVICEactive cathodal tDCS

active cathodal tDCS with memory task

Sponsors

The University of Texas at Dallas
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Age: 18-35 years Native English Speaker

Exclusion criteria

* History of severe head injuries, epileptic insults, or heart disease. Severe psychiatric disorders and severe untreated medical problems. Contraindications for tDCS (pregnant women, implanted devices)

Design outcomes

Primary

MeasureTime frameDescription
Associative Memory assessed by a Face Name Associate Memory experimentAssociate Memory is assessed after a 10 minutes break following the study phaseChanges in performance in the Face Name Associate memory task is compared between the 2 groups (1. Real tDCS+ Face Name Associate memory task & 2. Sham tDCS+ Face Name Associate memory task) to investigate the influence of tDCS on Associative Memory.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026