Atrial Fibrillation, Coronary Artery Disease
Conditions
Keywords
left atrial appendage occlusion, antithrombotic therapy, atrial fibrillation, percutaneous coronary intervention, drug eluting stent
Brief summary
This study will retrospectively review and compare clinical outcomes between left atrial appendage occlusion with dual antiplatelet therapy versus conventional antithrombotic therapy in patients with atrial fibrillation undergoing drug-eluting stent implantation.
Detailed description
Composite of stroke and major bleeding will be compared after adjusting those groups using inverse probability weighted model.
Interventions
PROCEDUREACP or Watchman
Left atrial appnedage occlusion using ACP or Watchman
Sponsors
Severance Hospital
Sejong General Hospital
Gachon University Gil Medical Center
Ulsan University Hospital
Korea University Anam Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patients with AF who underwent PCI and treated with LAAO and DAPT or conventional antithrombotic therapy
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Composite of stroke and major bleeding | From date of index procedure until the date of primary endpoint occur or date of last follow up, whichever came first, assessed up to 50 months | Primary endpoint is a composite of stroke and major bleeding. Stroke is defined as ischemic cerebrovascular event included both transient ischemic attack and ischemic cerebral infarction. Major bleeding event was defined as moderate or severe bleeding according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries criteria. |
Outcome results
None listed