Iliac Vein Compression Syndrome
Conditions
Brief summary
The aim of this study is to compare intravascular ultrasound with venography in the diagnosis and treatment of iliac vein compression syndrome.
Interventions
None listed
Sponsors
Shanghai Zhongshan Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Age: 18 to 90 years * Willing to participate in and sign the informed consent * Patients with suspicious iliac vein stenosis or compression presented by preoperative magnetic resonance venography (MRV) * Patent common femoral vein and/or femoral vein of the study leg * Undergoing iliofemoral venography with the intend to treat potential iliac vein compression syndrome
Exclusion criteria
* Not providing informed consent * Venous compression caused by pelvic tumors or fibroid uterus * Previous stent implantation or venovenous bypass surgery of the study leg * Known metal allergy precluding the possibility of stent implantation * Known iodine allergy or severe renal insufficient function which are unsuitable for venography * Pregnant or planning to be pregnant recently * Acute deep vein thrombosis or tumor thrombus involving the study leg * Know history of thrombophilia (e.g. protein C or S deficiency, anti-thrombin III deficiency, etc ) * Any concurrent disease, for example, heart failure, might make the patients unsuitable for surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage diameter reduction | 1 month | Compare the percentage diameter reduction measured by intravascular ultrasound (IVUS) and venography |
| Percentage area reduction | 1 month | Compare the percentage area reduction measured by IVUS and the calculated percentage area reduction measured by venography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| CEAP score | 18 months | Improvement in Clinical, Etiology, Anatomy, Pathophysiology (CEAP) score |
| Primary patency | 18 months | Primary patency can be defined as without additional revascularization of the target lesions, the target vessels are still patent which measured by ultrasound or magentic resonance venography (MRV) and the diameter reduction is \<50% during follow-up period. |
| Secondary patency | 18 months | Secondary patency can be defined as: with additional revascularization of the target lesions after the first surgery in our department, the target vessels are still patent which measured by ultrasound or magentic resonance venography (MRV) and the diameter reduction is \<50% during follow-up period. |
Countries
China
Contacts
Primary ContactZhenyu Shi, Doctor
Backup ContactYong Ding, Master
Outcome results
None listed