The Relationship Between Morbid Obesity and Carotid Artery Stenosis

The Relationship Between Morbid Obesity and Carotid Artery Stenosis - a Comparative Prospective Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03306771

Enrollment

Registered

2017-10-11

Start date

2018-06-30

Completion date

2020-07-31

Last updated

2018-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid Artery Diseases, Metabolic Syndrome, Morbid Obesity

Keywords

Morbid Obesity, Carotid Stenosis, Metabolic Syndrome

Brief summary

The correlation between metabolic syndrome and carotid artery stenosis is well established. The purpose of this study is to evaluate the relationship between morbid obesity and carotid artery stenosis.

Detailed description

The investigators hypothesis is that there is a direct relationship between morbid obesity and carotid artery stenosis. The investigators hypothesize that metabolic/Bariatric surgery improves the stenosis in the carotid artery. This is a prospective comparative study on the candidates for metabolic/Bariatric surgery in the bariatric center, Emek Medical Center, Afula, Israel. The investigators will compare the candidate for metabolic surgery with metabolic syndrome risk factors to the ones without metabolic syndrome risk factors. The assessment of the carotid artery will be done by Ultrasound Doppler before surgery and 6, 12 and 24 month post surgery.

Interventions

DIAGNOSTIC_TESTUltrasound Duplex

The two groups will have Ultrasound Duplex before bariatric surgery, and 6,12 and 24 months post surgery

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

• Candidates for first bariatric surgery

Exclusion criteria

* Smokers or past smokers * Patients who are post carotid artery intervention

Design outcomes

Primary

Measure	Time frame	Description
Correlation between morbid obesity and carotid artery stenosis	24 months post surgery	Evaluate the correlation between the two in order to identify high risk patient for carotid stenosis without metabolic syndrome risk factors

Secondary

Measure	Time frame	Description
Changes in Intimal -media thickness	Before bariatric surgery, and 6,12,24 months after the surgery	To compare the baseline Intimal-media thickness before surgery to the one post-surgery by the use of Ultrasound
Changes in the carotid artery velocity	Before bariatric surgery, and 6,12,24 months after the surgery	To compare the baseline carotid artery velocity before surgery to the one post-surgery by the use of Ultrasound Doppler

Contacts

Primary ContactUri Kaplan, MD

kaplanuri@gmail.com972-50-5315311

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026