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Influence of Sagittal Imbalance of the Spine on Gait Pattern in Adult Spinal Deformity

Influence of Sagittal Imbalance of the Spine on Gait Pattern in Adult Spinal Deformity

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03304405
Enrollment
15
Registered
2017-10-09
Start date
2016-06-01
Completion date
2017-06-01
Last updated
2020-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult Spinal Deformity

Keywords

ASD

Brief summary

This study intends to investigate the changes in gait pattern in adult spinal deformity (ASD) patients with sagittal imbalance. It will investigate the gait kinematics in patients who have a mismatch of their spinopelvic parameters, and a positive sagittal balance. The investigators hypothesise that patients with abnormal spinopelvic parameters may demonstrate a pathological gait pattern.

Detailed description

With an ageing population, ASD presents as a significant health issue with increasing incidence. Most of the earlier literature concentrated on radiographic measurements of the deformity in the coronal plane, and its surgical correction. However, recent publications have demonstrated that sagittal spinopelvic alignment plays a critical role in pain and disability in patients with ASD, and is a primary determinant of health related quality of life measures. There is substantial evidence that restoration of these parameters after spinal reconstructive surgery is correlated with good clinical outcome. Maintenance of the ideal sagittal alignment allows an individual to maintain an erect posture with minimal energy expenditure. When there is progressive loss of lumbar lordosis, compensatory mechanisms involving the pelvis, hips and knees occur to extend adjacent segments of the kyphotic spine to allow for compensation of anterior translation of the axis of gravity. However, this compensatory mechanism may potentially result in adverse effect. One of the main disabilities in ASD patients with sagittal imbalance is their decreased walking tolerance. The change in the spinal alignment along with these compensatory mechanisms may result in an inefficient gait worsening their walking tolerance. Few studies in the literature have investigated the changes in gait pattern in patients with sagittal imbalance. Of those, the patient group was heterogeneous, and the only criterion of sagittal imbalance was a positive sagittal vertical axis (SVA), which the investigators now know is not a complete assessment of the sagittal alignment. The investigators propose to study the change in gait pattern in individuals with abnormal spinopelvic parameters, and how this may affect their quality of lives.

Interventions

DIAGNOSTIC_TESTGait Analysis

All patients will undergo gait analysis using reflective surface markers placed at different locations on the head, trunk, upper and lower extremities, and pelvis. All patients will complete an analog pain scale, Oswestry, and SRS-22 questionnaires. These are health-related quality of life questionnaires that provide subjective assessment.

Sponsors

The University of Hong Kong
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

All patients diagnosed with ASD, fulfilling the following radiographic criteria based on whole spine lateral film are eligible for recruitment: * SVA bigger than 47mm * Pelvic tilt (PT) bigger than 22deg * Pelvic incidence (PI) - lumbar lordosis (LL) bigger than 11deg

Exclusion criteria

* If the aetiology of the ASD of the patient is neuromuscular origin * other pathologies that may affect their gait such as previous trauma or surgeries to the pelvis or the lower limbs and joint replacements * inability to walk without aids for short distances

Design outcomes

Primary

MeasureTime frameDescription
Evaluate the effect of sagittal imbalance on the gait cycle using reflective surface markers1 yearTo evaluate the effect of sagittal imbalance on the gait cycle using reflective surface markers

Secondary

MeasureTime frameDescription
Investigate the difference in gait kinematics between normal and abnormal sagittal balance using reflective surface markers1 yearTo investigate the difference in gait kinematics between normal and abnormal sagittal balance using reflective surface markers
Investigate the efficiency in gait differences between normal and abnormal sagittal balance using reflective surface markers1 yearTo investigate the efficiency in gait differences between normal and abnormal sagittal balance using reflective surface markers
Investigate different muscle recruitment in gait cycles between normal and abnormal sagittal balance using a submaximal graded exercise test1 yearTo investigate different muscle recruitment in gait cycles between normal and abnormal sagittal balance using a submaximal graded exercise test

Countries

Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026