Acute Kidney Injuries, Chronic Kidney Disease, Quality of Life, Renal Replacement Therapy
Conditions
Keywords
acute kidney injury, quality of life, Renal replacement therapy, Intensive care unit
Brief summary
Acute kidney injury (AKI) involves poor prognosis in ICU patients. The renal prognosis at long term is unknown. The study will determine chronic kidney injury incidence and quality of life, five years after AK during ICU stay.
Detailed description
Prospective study. All patients who participated ELVIS study (clinical trials: 00875069) can be enrolled in SURIA. Patients are contacted by telephone. Investigator delivery objective and honest information. If patients accepts the study, answers will be collected. Collected data are: creatinine serum, two surveys (quality of life and activities of daily living), date of onset of renal replacement therapy.
Interventions
None listed
Sponsors
University Hospital, Clermont-Ferrand
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
ICU Patients included in ELVIS study, AKI requiring renal replacement therapy Length of ICU stay ≥ 48h
Exclusion criteria
Pregnant or nursing woman's job
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of chronic kidney disease | 5 years after the first acute kidney injury requiring renal replacement therapy | incidence of chronic kidney disease in patients who had an acute kidney injury during their ICU stay and requiring an renal replacement therapy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| severity of CKD according to the International Classification of Chronic Kidney Disease | 5 years after the first acute kidney injury requiring renal replacement therapy | Kidney function will be measured by creatinine serum or chronic dialysis or kidney transplantation |
| impact of the renal replacement therapy on long-term renal function | 5 years after the first acute kidney injury requiring renal replacement therapy | Intermittent or continuous renal replacement therapy. Data collected in the database from ELVIS study. Kidney function will be measured by creatinine serum or chronic dialysis |
| quality of life | 5 years after the first acute kidney injury requiring renal replacement therapy | Quality of life will be assessed with the Q5D score |
| Activities of daily living | 5 years after the first acute kidney injury requiring renal replacement therapy | Activities of daily living will be assessed with the Katz adjustment scales |
| Mortality | 5 years after the first acute kidney injury requiring renal replacement therapy | Mortality |
Countries
France
Contacts
Primary ContactPatrick LACARIN
Outcome results
None listed