Alveolar Ridge Abnormality
Conditions
Keywords
Alveolar cleft -Platelet rich fibrin- calcium phosphate
Brief summary
P- Maxillary alveolar cleft defects I- Platelet-rich fibrin (PRF) combined with biphasic calcium phosphate (BCP) C- Autogenous bone graft O- Outcome measure : bone height, bone volume, hospital stay, operation duration T- 6 months S- Randomized controlled clinical trial this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch.
Detailed description
this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch
Interventions
OTHERPRF/ BCP
Platelet rich fibrin combined with biphasic calcium phosphate(experimental group)
Bone obtained from the same individual who receiving the graft
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Eighteen patients will be divided into two equal groups. Each group comprises nine patients. Group A: Platelet-rich Fibrin combined with Biphasic Calcium Phosphate.(interventional group) Group B: autogenous bone graft (controlled group)
Eligibility
Sex/Gender
ALL
Age
8 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients suffering from maxillary alveolar cleft * Patients' age 8 years and older
Exclusion criteria
* Syndromic cases will be excluded * Patients suffering from platelets disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bone height | six months postoperative. | the vertical bone height measured from the most coronal level of the pyriform aperture to the most apical level of the bony bridge. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| bone volume | six months postoperative. | V= (A1xT) + ( A2 xT) + …….+ (An xT) where: V= volume A= area T= thickness of the axial C.T slice N=number of slices |
| operation duration | within 4 hours ( the actual number of hours will be determined intra-operative ) | It is the time elapsed between using the scalable for incision and the last stitch. It will be measured by watch in hours. |
| hospital stay | within 7 days | Number of days that patients spend in hospital. Measured by calendar, starting from time of admission ending with time of discharge |
Countries
Egypt
Outcome results
None listed