Amino Acid Metabolism
Conditions
Keywords
Amino acid uptake, Aging, Meat protein
Brief summary
The purpose of the project is to provide evidence for the use of hydrolysed meat protein (HMP) as a protein supplement for elderly who has difficulty meeting the recommended daily protein intake. The study will investigate how the meat protein derived amino acids (from either HMP, steak or minced meat) are absorbed and released into the blood circulation of elderly persons. Hereby, the study will explore the the anabolic potential of HMP compared with common meat products.
Interventions
DIETARY_SUPPLEMENTMeat protein absorption
Meat protein absorption when digested together with a full meal.
Sponsors
DC Ingredients
Bispebjerg Hospital
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
DOUBLE (Investigator, Outcomes Assessor)
Masking description
Outcome assessor and investigator will be blindet. Participants cannot be blindet, as they will consume three different meat products, that we cannot mask.
Intervention model description
Single-blindet randomized cross-over study
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy * Untrained
Exclusion criteria
* below 65 years of age * BMI above 30 * Smokers * Vegetarians * Subjects with diabetes or other metabolic diseases * Medical treatment affecting protein synthesis * Gastro-intestinal problems, reduced liver or kidney function, elevated blood pressure, atherosclerosis * More than 5 ours regular physical activity per week (except physical activity related to commuting)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| D5-phenylalanine appearance | 5 hours | D5-phenylalanine appearance in the blood circulation after meal consumption |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Insulin concentration | 5 hours | Insulin concentration in the blood circulation after meal consumption |
Countries
Denmark
Outcome results
None listed