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Ultrasonic Cardiogram Evaluate the Prognosis of Percutaneous Revascularization of Chronic Total Occlusions

Ultrasonic Cardiogram to Evaluate the Long-term Outcome and Prognosis of Coronary Artery Chronic Total Occlusions for Percutaneous Revascularization Versus Optimal Medical Treatment

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03300011
Enrollment
200
Registered
2017-10-03
Start date
2016-10-01
Completion date
2018-10-01
Last updated
2017-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Chronic Total Occlusion

Keywords

ultrasonic, chronic total occlusion, heart function

Brief summary

Chronic total occlusions (CTO) are encountered in almost one-fourth of patients undergoing coronary angiography. The presence of an untreated CTO has been related to adverse clinical prognosis, both in stable angina and acute myocardial infarction, and is often associated with persistent symptomatic angina. Depending on their symptomatic and functional status as well as anatomical complexity, CTO can be treated by optimal medical therapy only or therapy combined with coronary revascularization. This study designed to evaluate the safety and efficacy of coronary chronic total occlusion PCI by ultrasonic cardiogram.

Detailed description

UCEPPCIOCT maintains a prospective clinical registry of all individual who undergo cardiac angiography,PCI or optimistic medicine treatment. 1\. research objective to observe the changes of cardiac function postoperative PCI in patients with CTO and the incidence of major adverse cardiovascular events, and provide the reality basis for PCI strategy in clinical patients with CTO . 2. research content: follow up the patients with CTO by using echocardiography in preoperative and postoperative PCI in 1m, 3ms, 6ms, 12ms to assess the changes of cardiac structure and cardiac function. 2, comparison the 'incidence of major adverse cardiovascular events undergo PCI treatment in success and failure group in patients with CTO (such as severe angina attack, severe acute coronary syndrome, severe heart failure should be rehospitalized , fatal arrhythmia and sudden cardiac death, etc.)

Interventions

DEVICEstent

PTCA or PCI

Sponsors

Southeast University, China
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
OTHER
Masking
DOUBLE (Investigator, Outcomes Assessor)

Masking description

masking for Ultrasonic Cardiogram investigator

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

coronary artery of chronic total occlusion

Exclusion criteria

ACS in 3months; once PCI or CABG; AF

Design outcomes

Primary

MeasureTime frameDescription
cardiac death,postoperation 1yearpatients with CTO postoperative sudden death cause for acute myocardial infarction or severe arrhythmia
MACEpostoperation 1yearrecurrent severe angina, revascularization

Countries

China

Contacts

Primary ContactChen Lijuan, Ph.D
chenlijuan@seu.edu.cn15295583256
Backup ContactMa Genshan, Ph.D
magenshan@hotmail.com13002580569

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026