Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland

Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland - the STARR Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03299569

Acronym

STARR

Enrollment

800

Registered

2017-10-03

Start date

2016-07-29

Completion date

2028-12-31

Last updated

2026-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Infarction, Takotsubo Cardiomyopathy

Brief summary

Acute stress-induced (Takotsubo cardiomyopathy) presents like a heart attack and is triggered by intense emotional or physical stress. Although coronary arteries are unobstructed, it has been suggested that the risk of death is similar to a myocardial infarction. The purpose of the STARR study is to identify all cases of Takotsubo in Scotland since 2010 and assess its epidemiology and outcomes.

Detailed description

Public Health Scotland will identify all patients centrally coded under codes I42.8 (Other cardiomyopathies), I42.9 (Cardiomyopathy, unspecified) and I51.8 (Other ill-defined heart diseases), using the Community Health Index (CHI) numbers from January 2010. All identified CHI numbers will be thereafter cross-checked with their clinical data at participating health boards to confirm a diagnosis of takotsubo cardiomyopathy and a registry of all confirmed Takotsubo cases will be established. Clinical data will be collected for all Takotsubo patients retrospectively and prospectively. This will be compared to two contemporaneous gender and age matched control populations: 1. a cohort of randomly selected individuals from the Scottish general population supplied by Public Health Scotland 2. patients with myocardial infarction (extracted through collaboration with, the High-STEACS investigators, NCT01852123). Electronic data linkage will be performed by Public Health Scotland to assess outcomes, prescribing and scores of prediction.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Inclusion criteria

* All patients diagnosed with Takotsubo cardiomyopathy

Exclusion criteria

* NA

Design outcomes

Primary

Measure	Time frame	Description
Mortality and morbidity of takotsubo syndrome	13 years	To use a nation-wide cohort (and matched national-wide control populations) to establish the all-cause mortality and consequent all cause hospitalisation rates

Secondary

Measure	Time frame	Description
Specific causes of mortality and morbidity of takotsubo syndrome	13 years	To use a nation-wide cohort (and matched national-wide control populations) to establish the specific causes of mortality and morbidities requiring subsequent hospitalisation

Countries

United Kingdom

Contacts

CONTACTDana Dawson, MD, MRCP

dana.dawson@abdn.ac.uk01224 437969

CONTACTAmelia Rudd, HND

a.e.rudd@abdn.ac.uk01224 559573

PRINCIPAL_INVESTIGATORDana Dawson, MD, MRCP

University of Aberdeen

Outcome results