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Caffeine for Preterm Infants With Apnea of Prematurity(AOP)

Caffeine for Preterm Infants With Apnea of Prematurity(AOP): a Randomized Controlled Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03298347
Enrollment
100
Registered
2017-10-02
Start date
2017-10-01
Completion date
2018-10-01
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apnea of Prematurity, Caffeine

Brief summary

Nowadays,caffein is commonly used for AOP, and it reduces the intubation rate in preterm infants. However, intubation is needed in about 20%-50% of partial neonates. How to reduce the intubation rate effectively is a challenge for neonatologists.

Detailed description

Less evidences about more dose of caffein used in preterm infants.

Interventions

DRUG80mg/kg of caffeine

80mg/kg of caffeine is given to treat AOP

DRUG20mg/kg of caffeine

20mg/kg of caffeine is given to treat AOP

Sponsors

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
1 Minutes to 1 Months
Healthy volunteers
No

Inclusion criteria

* gestational age less than 32 weeks; * appear AOP; * parents'consents are obtained.

Exclusion criteria

* major congenital abnormalities; * Parents' rejection

Design outcomes

Primary

MeasureTime frameDescription
the rate of AOPwithin 100 daysAOP appears again in preterm infants

Countries

China

Contacts

Primary ContactMa Juan, MD
416767068@qq.com18680887330
Backup ContactShi Yuan, MD;PhD
petshi530@vip.163.com13508300283

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026