Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment

Conditions

Acute Myocardial Infarction, Heart Failure

Keywords

acute myocardial infarction, heart failure, optimized treatment

Brief summary

The main purpose of this study is to build a multi-center, prospective and regionally representative acute myocardial infarction(AMI) cohort，and build a study platform for heart failure caused by AMI; To explore the 1 year incidence rate of heart failure after AMI given the optimized treatment and the treatment model affecting the incidence rate of heart failure, and finally to reduce the incidence rate of heart failure by 5%.

Detailed description

the study aim to enroll 12000 acute myocardial infartion (AMI) patients, including ST-segment elevation myocardial infarction (STEMI) and non ST-segment elevation myocardial infarction (NSETMI), Patients were divided into two groups(optimized group and un-optimized group) according to treatment models they accepted in 20 reginally representative hosptials of China. whether optimizaed or not is judged by 4 four aspects,including emergency treatment procedure, pre-infusion medication, reperfusion strategy selection, and early rehabilitation after reperfusion.Patients were followed at 1 month, 6 months and 12 months. The physical condition and clinical events(heart failure, death, re-infarction, revascularization, apoplexy, malignant arrhythmias, bleeding events, other adverse events)were collected at follow up.

Hou X, Liu J, Zhang J, Wang X, Liu Q, Wang S, Yang X, Zhang Y, Zhang W, Chen S, Sun Y, Wu J.

2026-01-06

10.1016/j.hrtlng.2025.102716

Pseudo-targeted metabolic profile differences between emergency patients with type 1 and type 2 myocardial infarction diagnosed by optical coherence tomography.

Wang J, Li Z, Yang G, Fang C, Yin Y, Zheng Z, Wang H, Fang S, Dai J, Wang S, Yang S, Yu B.

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Zeng M, Zhao C, Bao X, Liu M, He L, Xu Y, Meng W, Qin Y, Weng Z, Yi B, Zhang D, Wang S, Luo X, Lv Y, Chen X, Sun Q, Feng X, Gao Z, Sun Y, Demuyakor A, Li J, Hu S, Guagliumi G, Mintz GS, Jia H, Yu B.

2022-12-1432 citations

10.1016/j.jcmg.2022.10.023

A Novel Risk Score to Predict In-Hospital Mortality in Patients With Acute Myocardial Infarction: Results From a Prospective Observational Cohort

Lulu Li, Xiling Zhang, Yini Wang, Xi Yu, Haibo Jia et al. (14 authors)

Frontiers in Cardiovascular Medicine2022-04-074 citations

10.3389/fcvm.2022.840485

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* age≥18 years * diagnosed acute myocardial infarction * signed the informed consent form

Exclusion criteria

* AMI is caused by surgery, trauma, gastrointestinal bleeding or complications of PCI; * AMI occurred in patients who have been hospitalized for other reasons; * patients with previous history of chronic heart failure; * researchers judging that patient's compliance was poor and could not complete the study according to the requirements. * life expectancy is less than 12 months; * heart transplant patients; * patients with tumors;

Design outcomes

Primary

Measure	Time frame	Description
incidence rate of heart failure	12th month after diacharge	incidence rate of heart failure of acute myocardial infarction at 12th month

Secondary

Measure	Time frame	Description
MACCE rate	12th month after diacharge	the major adverse cardiac celebral events including death,reinfarction,
bleeding rate	12th month after diacharge	the incidence rate of bleeding
severe adverse drug reactions	12th month after diacharge	severe adverse drug reactions at 12th month

Countries

China

Outcome results