Patients With Ocular Neuropathic Pain: Description of Pain and Impact on Their Quality of Life

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03296111

Acronym

QUALVIDON

Enrollment

Registered

2017-09-28

Start date

2017-05-04

Completion date

2019-10-28

Last updated

2019-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye Syndromes, Neuralgia, Pain, Quality of Life

Brief summary

Some patients with dry eye may have severe disabling neuropathic pain. They describe spontaneous pain, dysesthesia, hyperalgesia or even allodynia. It is classical to note an important discordance between the high intensity of the symptoms and the poverty of the clinical signs. These pains are often unrecognized and therefore often not sufficiently treated. A significant impact on patient's quality of life may occur. The concept of ocular neuropathic pain being relatively recent, few studies have focused on the subject at present. Our study aims to shed light on these pains in patients consulting for dry eyes at the Ophthalmological Foundation A. de Rothschild. The objective of our study is to describe precisely the characteristics of neuropathic eye pain and the visual, general and psychological repercussions in these patients.

Interventions

OTHERQuestionnaires on pain and quality of life

Patients will be asked to complete several questionnaires about their pain and the impact on their quality of life. They will complete the questionnaires in the ophthalmology consultation room or at home and return it by mail (or present it at the next consultation). Patients will be asked to complete several questionnaires : * Questionnaire about the characteristics of ocular neuropathic pain (7 items) * DEQ-5 (Dry Eye Questionnaire) * ODI (Ocular Surface Disease Index) * BPI (Brief Pain Inventory) * HADS (Hospital Anxiety and Depression Scale)

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient aged 18 years or older, * Presenting at least one of the following symptoms: spontaneous pain, burning sensation in eye, dysesthesia, allodynia, hyperalgesia * French language-skills

Exclusion criteria

* Severe corneal or palpebral damage explaining current pain

Design outcomes

Primary

Measure	Time frame
Scores obtained with each questionnaires.	baseline

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026