Acute Respiratory Distress Syndrome (ARDS), Red Blood Cells(RBC)
Conditions
Brief summary
Acute respiratory distress syndrome (ARDS) in neonates has been defined in 2017. The death rate is over 50%.There are no special treatments for acute respiratory distress syndrome.
Detailed description
Acute respiratory distress syndrome (ARDS) is one of the serious complications in critically ill neonates. It can result in severe hypoxemia refractory to mechanical ventilation. There are few options for mechanical ventilation for such situations such as high frequency oscillation ventilation and extracorporeal membrane oxygenation. The aim of the present study is to determine whether transfusion of red blood cells can decrease the mortality in neonate with ARDS.
Interventions
OTHERconventional treatment with RBC transfusion
Besides conventional treatment, neonates is given RBC transfusion.
OTHERconventional treatment
neonates is treated with conventional treatment.
Sponsors
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Minutes to 1 Months
Healthy volunteers
No
Inclusion criteria
* diagnosed with neonatal ARDS. * informed parental consent has been obtained
Exclusion criteria
* major congenital malformations or complex congenital heart disease * transferred out of the neonatal intensive care unit without treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| death rate | within 100 days | neonate died due to respiratory failure |
Countries
China
Contacts
Primary ContactMa Juan, MD
Backup ContactMa Juan, MD
Outcome results
None listed