Evolution of the Profile of Infectious Endocarditis in France in 2008 (EI2008)

Evolution of the Profile of Infectious Endocarditis in France in 2008

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03295045

Acronym

EI2008

Enrollment

484

Registered

2017-09-27

Start date

2007-12-01

Completion date

2010-12-31

Last updated

2017-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infective Endocarditis

Brief summary

Infective endocarditis (IE) is a rare (30 cases / million / year in France) and serious (20 % of deaths during hospitalization) disease . Its epidemiological profile was considerably modified these last years.New predisposing factors appeared, due to increasing number of patients wearing valvular prosthetics. The purpose of this study is to realize in 2008 a new observational study on populational basis to describe and analyze the evolution of the epidemiology of IE in France, compared to previous studies conducted in 1991 and 1999.

Detailed description

It is a prospective observational study based on a population of 25 million inhabitants. The cases are recruited over a one year period, from January 1st till December 31st, 2008, in six regions of France (Rhône-Alpes, Paris et Petite Couronne, Lorraine, Franche-Comté, Marne, Languedoc-Roussillon) and in the department of Ille-et-Vilaine. The IE cases are declared by clinicians taking care of the patients, microbiologists and cardiac ultrasonographists.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Major Patient * Supported in one of the participating centers * The application of diagnostic classification criteria of Duke modified by Li is carried out after collection of all the data at the output of the patient. Will be included in the observatory that patients meeting criteria for definite or possible endocarditis. * Affiliated with the French social security regime

Exclusion criteria

* Patients not living in one of the studied regions

Design outcomes

Primary

Measure	Time frame	Description
Mortality	1 year	Vital status

Secondary

Measure	Time frame	Description
Frequency of antibiotic resistance by the germs (streptococci and staphylococci)	during the hospitalization, 1 year maximum	antibiotic treatments and outcome

Outcome results