Chronic Lymphoid Leukaemia
Conditions
Keywords
Chronic lymphocytic leukemia, Observational study
Brief summary
Brief Summary: The purpose of the OFICE registry is to characterize and describe the CLL patients' population from the Finistere area and evaluates the association between different patient characteristics, prognosis and treatment patterns. Detailed Description: OFICE is a single center, prospective, observational registry of CLL patients designed to provide a general description of the CLL patients' population from the Finistere area, France. The registry will also provide information on the association of cytogenetic and immunophenotypic characteristics with disease progression, as well as treatment patterns and healthcare resource utilization. These data will be accessible and beneficial for researchers and physicians and will help guide clinical practice and future clinical or fundamental studies.
Interventions
None listed
Sponsors
University Hospital, Brest
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age of at least 18 years * Clinical diagnosis of CLL/SLL that meets published diagnostic criteria (Hallek 2008) * Willing and able to provide informed consent * Willing and able to provide blood sample at time of enrollment
Exclusion criteria
* Diagnosis of other B-cell malignancies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence | Year 0 (Y) | Clinical data |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence | Year 0 | Clinical and biological data |
| Description of baseline clinical-biological | Year 0, Year 1, Year 2, Year 3 | Clinical data, complete blood count, Matutes score and parameters, cytogenetic, IgVH mutations, CD38 (%), medical treatment will be collected |
Countries
France
Contacts
Primary ContactYves Renaudineau
Outcome results
None listed