Exercise Training on Metabolic Syndrome Severity in Employees

Conditions

Metabolic Syndrome

Keywords

metabolic syndrome, exercise training, employees, workplace, operational health service

Brief summary

Hypothesis: An occupational 6 months physical exercise training will lead to better health behaviour and improve the severity of the metabolic syndrome. 312 subjects will be assigned to either an intervention or a waiting-control-group. The intervention group will receive instructions with the aim to perform 150 min exercise training per week. Exercise consists of endurance, strength and coordination training. A feedback system guided by sports scientists will be installed for all subjects in the intervention group using activity monitoring (wearable). After 6 months training subjects from the intervention group will be assigned to one of the following groups for follow-up observation from month 6 to months 12: * training with personal/individual feedback from sport scientist * training with automated feedback using activity monitoring Tools (wearable) * training without further feedback Subjects assigned to the control group will be provided with information on low intensity motion exercises. After 6 months in the control group subjects will be provided with the same exercise intervention as the intervention for a duration of 6 months. Study visits will be conducted at month 0, month 6, month 12, and a long-term follow-up at month 24..

Sven Haufe, Katharina Luise Hupa‐Breier, Pauline Bayerle, Hedwig Theda Boeck, Simone Rolff et al. (20 authors)

Clinical and Translational Gastroenterology2021-06-0116 citations

10.14309/ctg.0000000000000371

Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.

Sven Haufe, Kai G. Kahl, Arno Kerling, Gudrun Protte, Pauline Bayerle et al. (21 authors)

Frontiers in Psychiatry2020-06-1813 citations

10.3389/fpsyt.2020.00562

Telemonitoring-supported exercise training, metabolic syndrome severity, and work ability in company employees: a randomised controlled trial.

Haufe S, Kerling A, Protte G, Bayerle P, Stenner HT, Rolff S, Sundermeier T, Kück M, Ensslen R, Nachbar L, Lauenstein D, Böthig D, Bara C, Hanke AA, Terkamp C, Stiesch M, Hilfiker-Kleiner D, Haverich A, Tegtbur U.

2019-06-1344 citations

10.1016/s2468-2667(19)30075-1

Interventions

BEHAVIORALExercise training group

Exercise training will consist of 3 - 6 sessions per week and will cumulate in 150 min net exercise time per week. Heart rates during exercise sessions will be monitored with the aim of physical activities at moderate-intensity. Exercises will be individualized to reach the best possible improvements to the cardiovascular and musculoskeletal system. Possible disciples will include but are not limited to: cycling, rowing (ergometer), swimming, walking, nordic-walking, running, arm-cycle-ergometer or cross-trainer as well as fitness courses offered from occupational or private providers. Everyday activities which reach an effective heart rate range can account for exercise training on a home-based basis . Advise on complementary individual strength and coordination exercises will be added to the training program. A nutrition analyses will be completed by every subject to account for special needs of the metabolic syndrome.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* 3 out of 5 parameters of the metabolic syndrome

Exclusion criteria

* ongoing participation in occupational health service * clinical relevant acute or chronic infections * pregnancy * surgery dating back less than 8 weeks * artificial joint replacement dating back less than 6 months * tumor disease dating back less than 5 years * every other disease or relevant functional disorder not allowing to participate in regular physical exercise

Design outcomes

Primary

Measure	Time frame	Description
Change from baseline in Metabolic Syndrome (MetS) -Z-score	6 months 12 months, 24 months	Z-Score (arbitrary unit, ranging from -2 to 2), assessed and calculated from the 5 established components of the metabolic syndrome: triglycerides, HDL cholesterol, fasting glucose, waist circumference, and systolic blood pressure.

Secondary

Measure	Time frame	Description
Change from baseline in Health-related quality of live: score of SF36 questionnaire	6 months, 12 months, 24 months	score of SF36 questionnaire (outcomes: physical component score: Minimum 1 Point, Maximum 100 Points, mental component score: Minimum 1 Point, Maximum 100 Points)
Change from baseline in Pmax	6 months	Maximum workload reached in an graded exercise test (watt/kg Body Weight).
Change from baseline in Body weight	6 months	kg
Change from baseline in Work-Ability-Index (WAI)	6 months, 12 months, 24 months	score of WAI questionnaire, (Outcome work ability score: Minimum 1 Point, Maximum 49 Points)
Change from baseline in adherence to training program	6 months, 12 months, 24 months	percentage (%) of time (150 min per week) spend on exercising (minutes)
Change from baseline in Anxiety- and depression severity	6 months, 12 months, 24 months	Hospital Anxiety and Depression Scale, (outcomes: amxiety severity: Minimum 1 Point, Maximum 21 Points, Depression severity: Minimum 1 Point, Maximum 21 Points)
Change from baseline in body composition	6 months, 12 months, 24 months	fat mass (kg), fat free mass (kg), visceral fat mass (kg)

Countries

Germany

Outcome results

None listed