Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors

Evaluate the Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03288662

Enrollment

Registered

2017-09-20

Start date

2013-10-01

Completion date

2017-07-31

Last updated

2017-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thymoma

Keywords

Computed tomography, thymic epithelial tumors

Brief summary

the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue.

Detailed description

1. Introduction: the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue. 2. Materials and methods: 2.1. Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors 2.2. Time and Place: in Departement of CTVS, Military Hospital 103, Vietnam from 10/2013 to 7/2017. 2.3. methods: * study in chest CT scan: * Measure the maximun diameter of the tumor * The contour: smooth contour or irregular contour * The shape: round, oval and plaque base on the ratio between long axis and short axis of the tumor * Some other characteristics: Degree of enhancement, Level of drug absorbed, Calcification, Invasion the local organs and Capsular destruction. * Histopathological study: based on the 2004 WHO classification: * Thymoma: type A, AB, B1, B2, B3 * Thymic carcinoma * Data processing: use software Epi Info 2000. 3. Expectation of results * Relationship between the size and histopathological type of thymic epithelial tumors. * Comparison of some characteristics of the tumor on preoperative chest CT scans and histopathological type of thymic epithelial tumors

Interventions

OTHERCT and histopathological classification

Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors. Base on the characteristics in Chest CT scan in each postoperative histopathology results.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Intervention model description

Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors

Eligibility

Sex/Gender

ALL

Age

21 Years to 71 Years

Healthy volunteers

Inclusion criteria

* All of patient have a chest CT scan pre-operation and a result of thymic epithelial tumors postoperative histopathology

Exclusion criteria

* Incomplete or loss the CT and postoperative histopathology

Design outcomes

Primary

Measure	Time frame	Description
maximun diameter of the tumor	1 month	Measure the maximun diameter of the tumor in chest CT scan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026