Healthy
Conditions
Keywords
calcium carbonate, calcium phosphate, metabolic effects, human study, calcium and phosphorus metabolism
Brief summary
The study was conducted to investigate the metabolic effects of three different calcium compounds in healthy adults.
Interventions
DIETARY_SUPPLEMENTcalcium phosphate
DIETARY_SUPPLEMENTTricalcium Phosphate
DIETARY_SUPPLEMENTCalcium carbonate
DIETARY_SUPPLEMENTPlacebo
Sponsors
University of Jena
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* age 18 - 40 years
Exclusion criteria
* diseases of the gastrointestinal tract * pregnancy * the intake of any medication (e. g. for thyroid gland) * intake of dietary supplements
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum mineral concentration | after 4 weeks of each intervention | Calcium and Phosphate (and others) concentration in serum. |
| Stool mineral concentration | after 4 weeks of each intervention | Calcium and Phosphate concentration (and others) in stool from a three day stool collection |
| Urine mineral concentration | after 4 weeks of each intervention | Calcium and Phosphate concentration (and others) in urine from a three day urine collection |
| Lipids in blood | after 4 weeks of each intervention | Lipids and lipoprotein concentration in serum. |
| Sterols | after 4 weeks of each intervention | Neutrals sterols and bile acids in stool from a three day stool collection |
| Dietary intake | after 4 weeks of each intervention | Evaluation of the dietary intake using a three day weighed dietary record. |
Outcome results
None listed