Drug Induced Submental Ultrasound in Obstructive Sleep Apnea Patients

Correlative Analysis of Upper Airway Collapse in Sleep Endoscope and Submental Ultrasound

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03285451

Enrollment

100

Registered

2017-09-18

Start date

2017-05-01

Completion date

2020-05-01

Last updated

2017-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea

Keywords

Submental ultrasound, Obstructive sleep apnea

Brief summary

In this study, submental ultrasound during awake and simultaneous under Drug-induced sleep endoscopy is applied in the diagnostic workup of obstructive sleep apnea patients. The aim is to assess the tongue base thickness during awake and sleep with different head positions. By correlation with Drug-induced sleep endoscopy findings, more parameters could be used for evaluation and management of upper airway collapse in obstructive sleep apnea patients.

Detailed description

Obstructive sleep apnea (OSA) is a syndrome characterized by recurrent episodes of apnea and hypopnea during sleep that are caused by repetitive upper airway (UA) collapse and often result in decreased blood oxygen levels and arousal from sleep. Successful treatment lies in precise mapping the site of airway narrowing. Drug-induced sleep endoscopy (DISE) is a well described modality to mimic the dynamic change of UA in OSA patients during natural sleep. Nevertheless, the tongue base thickness (TBT), one of the important anatomic factors in OSA, is hard to evaluate under this method. Recently, submental ultrasound (US), the noninvasive and convenient tool, has been widely applied to measure the TBT in awake OSA patients, so as to predict the severity and relationship with UA collapse. However, few evidence has addressed the relationship between UA collapse and the TBT in different head positions, awake and sleep period In this study, submental US during awake and drug induced sleep period is applied in the diagnostic workup of OSA patients. By correlation with DISE findings, more parameters could be used for evaluation and management of upper airway collapse in OSA patients. Key Words: Submental ultrasound, Obstructive sleep apnea, Drug-induced sleep endoscopy

Interventions

DIAGNOSTIC_TESTsubmental ultrasonography

Submental ultrasound, the noninvasive and convenient tool, has been widely applied to measure the tongue base thickness in patients with obstructive sleep apnea, so as to predict the severity and relationship with upper airway collapse.

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Obstructive sleep apnea patients, age between 20-70

Exclusion criteria

* severe heart, lung, liver, and kidney comorbidity propofol or dexmedetomidine allergies (albeit rare)

Design outcomes

Primary

Measure	Time frame	Description
The value of drug induced sleep ultrasonography in patients with obstructive sleep apnea	May, 2017 to Aug, 2017	In this study, we proposed a novel method, drug induced sleep ultrasonography (DISU), which was applied to measure the tongue base thickness in OSA patients during drug induced sleep, so as to further understand the impact of dynamic change of tongue base thickness in OSA patients.

Countries

Taiwan

Contacts

Primary ContactMing-Chin Lan, MD

lanmingchin@gmail.com+886920734552

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026