Executive Dysfunction, Parkinson Disease
Conditions
Keywords
parkinson, executive dysfunction, attention, computer-based cognitive training
Brief summary
The current study adresses the effect of two different computer-based cognitive trianing programmes on attention and executive functions in patients with Parkinson's disease.
Detailed description
The current study adresses the effect of two different computer-based cognitive training programmes (Brain+ Evolution and Scientific Brain Training PRO) on attention and executive functions in patients with Parkinson's disease. The patients are assigned to one of three groups. Two training groups with each their programme, and a control Group. The training groups will train at home for 8 weeks with follow-ups every second week. The control group will not train at home, but will also receive a follow-up with computer-based stimuli (computerized Card game) every second week, to minimize the possibility that a possible effect is due to the follow-up's with a professional, and not due to the computer training at home.
Interventions
Computer-based cognitive programmes are computer programmes designed as games with the aim of training patients in certain cognitive domains.
Sponsors
Bispebjerg Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Outcomes Assessor)
Masking description
Before and after the intervention period, the patients are tested in a neuropsychological battery to asses their executive functioning. The tester is blinded to the Group allocation of the patients.
Intervention model description
Two intervention Groups training with each their computer-based cognitive programme, one control Group receiving no intervention except for the same amount of follow-ups as the two intervention Groups.
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with Parkinson's disease AND * Montreal cognitive assesment (MOCA)-score between 22-28 * Motorically cabable of using an iPad * Not receiving antipsychotic medicine * No comorbid diseases which might influence the level of executive functioning, for an example ADHD or acquired brain damage
Exclusion criteria
* People without Parkinson's disease * Parkinson's patients not included in the above inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| SDMT | 2 minutes | Symbol digit modalities test, neuropsychological test of processing speed |
| PDQ-39 | 20 minutes | Parkinson's disease questionnaire; daily functioning and well-being in Parkinson's disease |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Verbal fluency | 3 minutes | S-Words, animal-names and A/F-words |
| HADS | 10 minutes | Hospital anxiety and depression screening |
| Trail Making A and B | 5 minutes | Trail Making A and B, cognitive flexibility |
| Stroop colour/word test | 3 minutes | Stroop colour/Word test, respone inhibition |
| Digit span | 10 minutes | Digit span Wais-IV; Working memory |
Countries
Denmark
Outcome results
None listed