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Doppler Ultrasound in Early Detection of Diabetic Nephropathy Type 2 Diabetes Mellitus.

Role of Doppler Ultrasound in Early Detection of Diabetic Nephropathy in Patients With Type 2 Diabetes Mellitus.

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03284996
Enrollment
80
Registered
2017-09-15
Start date
2017-10-01
Completion date
2019-09-01
Last updated
2017-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Nephropathies

Brief summary

Doppler sonography provides an easily applicable, non-invasive, and well-established method for investigating renal morphologic characteristics and measuring vascular resistance in the renal parenchyma. Doppler are of strategic importance in providing qualitative and quantitative information about the renal vasculature, which can be obtained through the assessment of the resistive index.

Detailed description

Nephropathy is one of the most common long-term, life-threatening complications causing a high rate of morbidity and mortality among individual patients with type 2 diabetes. The onset and progression of nephropathy can be delayed by interventions, provided they are instituted early in the course of the disease. Doppler sonography allows non-invasive method for investigating renal hemodynamics. Renal resistive index measured using Doppler ultrasonography, reflects intra-renal vascular resistance. Although Doppler sonography clearly does not substitute for renal biopsy, several studies have suggested that it might aid in the management of established renal disease and provide an easily applicable and noninvasive method for investigating renal hemodynamics. Doppler sonography provides an easily applicable, non-invasive, and well-established method for investigating renal morphologic characteristics and measuring vascular resistance in the renal parenchyma. Doppler are of strategic importance in providing qualitative and quantitative information about the renal vasculature, which can be obtained through the assessment of the resistive index. It is one of the most sensitive parameters in the study of kidney diseases and allows us to quantify the changes in renal plasma flow . A normal resistive index is below 0.7 in adults and children who are six years of age or older.

Interventions

Examination of the whole cases & controls by doppler ultrasound to measure renal resistive index.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
25 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* 1\. Type 2 diabetic patients. 2. Serum creatinine \<1.2 mg/dl

Exclusion criteria

\- 1. patients with known history of renal disease or any systemic diseases with renal complications. 2\. Serum creatinine \>1.2 mg/dl

Design outcomes

Primary

MeasureTime frameDescription
Early detection of diabetic nephropathy in patients with type 2 diabetes mellitus by measuring changes in renal resistive index using Doppler ultrasonography2 yearsEarly detection of diabetic nephropathy in patients with type 2 diabetes mellitus by measuring changes in renal resistive index using Doppler ultrasonography

Contacts

Primary ContactHassan Ibrahim Megally, Professor
hasanibrahim48@aun.edu.eg00201006209845
Backup ContactAbolhassan Hasseeb Mohamed, Lecturer
abolhasan_96@aun.edu.eg00201009562059

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026