Identifying New Genetic Causes to Development Disorders

Identifying New Genetic Causes to the Disorders of Growth, Puberty and Sex Development

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03283852

Acronym

FORDEV

Enrollment

1100

Registered

2017-09-14

Start date

2017-02-21

Completion date

2027-02-21

Last updated

2024-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorders of Sex Development, Growth Disorders, Puberty Disorders

Brief summary

Disorders of growth, puberty and sex development can have genetic causes. The exome analysis could detect new mutations responsible for these disorders and the frequency of these mutations in these disorders, their association with other malformations.

Interventions

GENETICblood sample

search for genetic mutations

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* congenital growth hormone deficiency * puberty disorder * gonadal dysgenesis or anorchia * primary ovarian failure * disorder of sex development * subjects related to a patient with one of the above criteria

Exclusion criteria

* environmental or auto-immune cause

Design outcomes

Primary

Measure	Time frame	Description
mutation research	baseline	frequency of genetic mutation

Countries

France

Contacts

Primary ContactAmélie YAVCHITZ, MD, PHD

ayavchitz@for.paris01 48 03 64 54

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026