Effect of Dietary Sodium and Potassium Citrate on Renal Mineral Handling

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03281928

Enrollment

Registered

2017-09-13

Start date

2017-10-01

Completion date

2022-11-15

Last updated

2025-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Stone

Brief summary

This study intends to characterize the affect of sodium and potassium citrate in the diet on renal function.

Interventions

DIETARY_SUPPLEMENTSodium and Potassium Citrate

Sodium and potassium citrate levels will be altered in diet and renal mineral handling will be measured as compared to placebo.

DIETARY_SUPPLEMENTPlacebo

Sodium without Potassium Citrate

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

OTHER

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* age 18 - 70, approximately equal numbers of men and women * studied by endoscopy with complete papillary mapping and grading * stone formers

Exclusion criteria

* Patients with primary renal diseases or renal impairment (eGFR \< 90), or medical conditions such as diabetes, or systemic diseases or medications that alter calcium metabolism * Patients with known bladder voiding problems

Design outcomes

Primary

Measure	Time frame	Description
Urine Calcium levels	10 days	Amount of calcium in the urine will be measured

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026