Admission of Adult-onset Still Disease Patients in the ICU

Admission of Adult-onset Still Disease Patients in the ICU: a French Retrospective Multicentric Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03276650

Acronym

Still-ICU

Enrollment

Registered

2017-09-08

Start date

2017-09-01

Completion date

2018-08-01

Last updated

2018-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult-Onset Still Disease, Critically Ill

Brief summary

Since its first description in 1971, diagnosing adult-onset Still's disease (AOSD), a rare multisystemic disorder considered as a multigenic autoinflammatory syndrome, remains challenging. Rarely, AOSD may present severe systemic manifestations and require intensive care. The main purpose of the Stil ICU study is to make the first description of the epidemiology of critically ill AOSD patients. The investigators will use a retrospective cohort study design with dual recruitment strategies: (1) via the AOSD referral centres network and (2) via a French academic medical ICU network.

Interventions

OTHERdata collection

biological, administrative, clinical, outcome date

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* AOSD (history of newly diagnosed) * ICU admission between January 2001 and June 2017

Exclusion criteria

* adults under protection * admission in step-down unit

Design outcomes

Primary

Measure	Time frame	Description
number of patients	At inclusion	Number of patients fulfilling the inclusion criteria

Secondary

Measure	Time frame	Description
APACHE II	24hour after ICU admission	Acute Physiologic Assessment and Chronic Health Evaluation II
Mortality	through study completion, maximum 17,5 years after admission	Kaplan Meier
Number of rehospitalisation in ICU	through study completion, maximum 17,5 years after admission	need for critical care after the first hospitalisation in ICU
number of hospitalisation in internal medicine ward	through study completion, maximum 17,5 years after admission	number of hospitalisation in internal medicine ward after the first ICU stay
recurrent relapses	through study completion, maximum 17,5 years after admission	number of recurrent flares after the first hospitalisation in ICU

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026