Periodontoclasia, Gingiva; Injury, Condition, Blood Clot, Gingiva Disorder
Conditions
Keywords
PRF, I-PRF, Microneedle, Gingival Thickness, Injectable-Platelet-Rich-Fibrin, Platelet Rich Fibrin
Brief summary
The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival thickness without the need for surgical procedures
Detailed description
Due to the thin gingival phenotype, gingival recession is a problem. The investigators aimed to increase the gingival thickness using i-PRF with microneedle without considering surgical procedures, considering the positive effects of platelet concentrations on revascularization and wound healing in individuals with bone defect, fenestration and gingival thickness which are prone to gingival recession .
Interventions
OTHERI-PRF
Venous blood will be taken from the patient every session and I-PRF will be created in the centrifuge.I-PRF injected on one side of bilateral thin gingival thickness.Microneedle application plus I-PRF injected on the other side in patients with bilateral region with thin gingival phenotype.Apply once a week and one month after the end of the injections, the patient will be called to the control.
Sponsors
Bezmialem Vakif University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Intervention model description
Blinded, Parallel group, Randomized Controlled Trial
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Never smokers * Had no history of systemic disease * Aged ≥18 years old
Exclusion criteria
* Patients with a history of diabetes mellitus or systemic disease * Patients who were under any medication that was known to influence periodontal tissues * Patients with hormonal changes such as pregnancy or lactation * Toothless individuals * Patients who were clotting disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gingival thickness (mm) | 2 months | Change in clinical measures of gingival thickness |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Plaque Index (PI) | 2 months | Change in clinical measures of gingival parameters |
| Gingival Index (GI) | 2 months | Change in clinical measures of gingival parameters |
| Bleeding on probing (BOP) | 2 months | Change in clinical measures of gingival parameters |
| Clinical attachment level (CAL) | 2 months | Change in clinical measures of gingival parameters |
| Probing pocket depth (PD) | 2 months | Change in clinical measures of gingival parameters |
Countries
Turkey (Türkiye)
Outcome results
None listed