Lumbar Disc Herniation
Conditions
Brief summary
The endoscopic discectomy has rapidly developed and increased need by patients. This procedure is widely performed by interventional pain physicians as well as by spine surgeons because it requires no general anesthesia or admission to a hospital. Many studies were reported that corticosteroid injection can inhibit persistent postoperative pain in lumbar discectomy. However, data of perioperative epidural steroids after an endoscopic discectomy is lacking.
Detailed description
To examine whether corticosteroid administered epidural space in patients undergoing endoscopic lumbar discectomy reduces postoperative morphine consumption, back and leg pain relief, improves functional disability comparing to placebo
Interventions
DRUG40 mg Triamcinolone acetate 1 cc
40 mg Triamcinolone acetate 1 cc
DRUGPlacebos
no injected agent
Sponsors
Ramathibodi Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Lumbar disc herniation patient age 20-45 year-old who have symptom duration was at least 6 weeks and conservative treatment failed
Exclusion criteria
* Refuse to participate and inform consent, Previous spinal surgery, History of allergic to steroid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative morphine consumption | Post operative 24 hour of morphine consumption in mg |
Secondary
| Measure | Time frame |
|---|---|
| Visual analog score (back and leg) 0-10 | 1 day, 2, 6 ,12, 24 weeks |
| Oswestry disability index (ODI | 2, 6 ,12, 24 weeks |
| MacNab scores | 2, 6 ,12, 24 weeks |
Outcome results
None listed