Systemic Sclerosis
Conditions
Brief summary
Diffuse infiltrating pneumonia (DIP) is a severe complication of systemic sclerosis and one of the leading cause of death in this condition. The main objective of this study is to prospectively describe the evolution of DIP overtime and to find prognosis factors.
Interventions
OTHERlung function tests
Patients hospitalized realise a Resting pulmonary function tests (PFT) which include the assessment of ventilatory capacity: spirometry (forced expiratory flows and mobilisable volumes)
Sponsors
University Hospital, Lille
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* systemic sclerosis * Diffuse Infiltrating Pneumonia
Exclusion criteria
* infection * other lung diseases * non French native
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| composite criteria: forced vital capacity and CO diffusing capacity | At 24 months | Degradation of forced vital capacity (FVC) ≥10% and / or DLCO ≥15% of initial values at prospective follow-up at 24 months. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| composite criteria: forced vital capacity and CO diffusing capacity | At 12 months | Degradation of forced vital capacity (FVC) ≥10% and / or DLCO ≥15% of initial values at prospective follow-up at 12 months. |
Countries
France
Outcome results
None listed