Simultaneous Injection of Propofol and Rocuronium in Inducing General Anesthesia

Efficacy of Neuromuscular Blockade Before Facemask Ventilation in Inducing General Anesthesia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03270696

Enrollment

114

Registered

2017-09-01

Start date

2017-08-23

Completion date

2018-01-30

Last updated

2018-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia; Functional

Brief summary

This study is conducted to evaluate the efficacy of simultaneous injection of propofol and rocuronium in inducing general anesthesia.

Interventions

DRUGadministration of propofol and rocuronium

compare the tidal volume applied from starting facemask ventilation under 15cmH2O of PCV for 1 minute according to administrating propofol and rocuronium simultaneously, or ordinally

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients undergoing elective surgery requiring endotracheal intubation * ASA I, II, and III * above 20 years

Exclusion criteria

* refuse to enroll * patients with risk of aspirating gastric contents * patients in whom NMBs are contraindicated * patients with predictors of difficult mask ventilation

Design outcomes

Primary

Measure	Time frame	Description
mean tidal volume	from starting facemask ventilation for 1 minute	mean tidal volume of facemask ventilation in 1 minute

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026