Parameters of Neurological Deficit After Thoracolumbar Fractures

Radiological Parameters Predicting Neurological Injury After Thoracolumbar Spinal Fractures

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03269851

Enrollment

160

Registered

2017-09-01

Start date

2018-11-01

Completion date

2020-03-21

Last updated

2021-07-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

SPINAL Fracture

Keywords

neurological deficit

Brief summary

To detect Radiological parameters affecting neurological injury after thoracolumbar spinal fractures.

Detailed description

Thoracolumbar spine fractures are the most common spinal column fractures. High activity and lack of stability make it more prone to fractures. Many studies have attempted to determine whether the neurological deficit in such fractures is related to spinal canal stenosis or other parameters observed on axial computed tomography (CT). However, this relationship remains controversial. Few reports shed light on the relation between different imaging parameters like sagittal alignment, vertebral body compression, canal stenosis, and type of fracture according to AO classification with the severity of nerve damage. These four radiographic parameters will be tested as expected risk factors for the neurological deficit in thoracolumbar fractures.

Interventions

RADIATIONcomputed tomography

ct will be done to detect radiological risk factors for neurological deficits after thoracolumbar fractures

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Any patient with Acute (within one month) thoracolumbar spine fracture above 18 years old with or without neurological deficit 2. In orthopaedics and trauma department of Assiut university hospital from 1st of November 2018 to 31 st of October 2019.

Exclusion criteria

* Patients younger than 18 years old. * Patients suffering from preoperative neurological diseases that hinder our examination like peripheral neuropathy or previous strokes. * Obtuned patients who cannot be properly examined like those with low GCS score. * Patients with old thoracolumbar fractures more than one month duration. * Patients with pathological spine fractures like those with osteoporosis and cancer metastasis. * Patients with fracture type A0 according to AO classification.

Design outcomes

Primary

Measure	Time frame	Description
To Measure spinal canal stenosis by cubic cm	one year	CT-Radiological parameters measured in patients with or without thoracolumbar fractures .
To measure sagittal alignment of vertebral column by cobb angle	one year	CT-Radiological parameters measured in patients with or without thoracolumbar fractures
To measure vertebral body compression by cm	one year	CT-Radiological parameters measured in patients with or without thoracolumbar fractures
To measure type of fracture according to AO classification	one year	CT-Radiological parameters measured in patients with or without thoracolumbar fractures

Secondary

Measure	Time frame	Description
Proportion of Neurological deficit among patients with thoracolumbar spine fractures.	one year	Number of patients with neurological deficit to the total number of patients with thoracolumbar spine fractures.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026