Skip to content

Age Gene/Environment Susceptibility Reykjavik Study

Association of Pre-diagnostic Vitamin D Levels and Survival in Older Individuals With Cancer

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03269656
Acronym
AGES
Enrollment
5764
Registered
2017-09-01
Start date
2002-01-01
Completion date
2014-12-31
Last updated
2017-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neoplasms

Keywords

Vitamin D, Cancer, Survival

Brief summary

5764 men and women in Iceland, aged 66 to 96 years entered the Ages Gene/Environment Susceptibility (AGES) - Reykjavik Study. Serum 25(OH)D was measured in 5,519 of all 5,764 (96%) participants at study entry in year 2002 through 2006. The main emphasis was on exploring whether pre-diagnostic serum levels of 25(OH)D were associated with survival after cancer diagnosis.

Interventions

None listed

Sponsors

University of Iceland
CollaboratorOTHER
Icelandic Heart Association
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
66 Years to 98 Years
Healthy volunteers
No

Inclusion criteria

* To participate in the AGES-Reykjavik study

Exclusion criteria

* To be diagnosed with cancer before study entry

Design outcomes

Primary

MeasureTime frameDescription
Overall survivalFrom date of diagnosis until death or censored at end of the follow-up (December 31, 2014)The association between pre-diagnostic 25(OH)D levels in cancer patients and overall survival
Cancer survivalFrom date of diagnosis until cancer death or censored at the end of the follow-up (December 31, 2014)The association between pre-diagnostic 25(OH)D levels in cancer patients and cancer survival

Secondary

MeasureTime frameDescription
Cancer diagnosisFrom date of blood draw (study entry) until cancer diagnosis, death or end of the observation period (December 31, 2014) whichever occurred firstThe association between pre-diagnostic 25(OH)D levels and cancer risk

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026