Healthy, Heart Failure With Normal Ejection Fraction, Mixed Connective Tissue Disease, Pulmonary Hypertension, Systemic Sclerosis
Conditions
Brief summary
Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure \>=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The investigators are establishing a biobank to collect samples (blood, urine, stool) from patients with pulmonary hypertension, patients at high risk for pulmonary hypertension, healthy controls, and patients undergoing right heart catheterization. Specimens will be stored for future investigations.
Interventions
OTHERNo intervention. Biospecimen collection only
Biospecimen collection
Sponsors
Louisiana State University Health Sciences Center in New Orleans
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of pulmonary hypertension and followed at the Comprehensive Pulmonary Hypertension Center OR * Diagnosis of systemic sclerosis and followed at the Comprehensive Pulmonary Hypertension Center OR * Diagnosis of mixed connective tissue disease and followed at the Comprehensive Pulmonary Hypertension Center OR * Undergoing outpatient right heart catheterization
Exclusion criteria
* Age\<18 * Pregnant * Unable to understand English * Currently incarcerated * Unwilling or unable to sign informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Collection of biospecimens | 10 years | Biospecimen collection only |
Countries
United States
Contacts
Primary ContactMatthew R Lammi, MD, MSCR
Outcome results
None listed