Idiopathic Pulmonary Fibrosis
Conditions
Keywords
Idiopathic pulmonary fibrosis, 3 minutes sit-to-stand test, Interindividual reproductibility
Brief summary
This study is designed to evaluate the reproductibility and the performance of the 3 minutes sit-to-stand test in patients with idiopathic pulmonary fibrosis. To do this, the investigators are recruiting 40 patients with idiopathic pulmonary fibrosis in 2 centers (Grenoble university hospital and Lyon university hospital). Patients had to achieve an effort test on a cycle ergometer. 2 visits are planned in the hospital. During each visit, patients will perform a 3 minutes sit-to-stand test, a 1 minute sit-to-stand test and a 6 minutes walk test. During the second visit, patients will also perform a 3 minutes sit-to-stand test with measurement of oxygen uptake. The investigators will then analyse the results by comparing numbers of cycle, functional response and symptoms during the 3 minutes sit-to-stand test of the 2 visits. The investigators will also compare the functional response obtained during the 3 minutes sit-to-stand test, the 1 minute sit-to-stand test and the 6 minutes walk test. Finally, the investigators will compare the maximal values of oxygen uptake, respiration rate and expired volume obtained during the 3 minutes sit-to-stand test to the effort test on cycle ergometer.
Interventions
DIAGNOSTIC_TEST3 minutes sit-to-stand test
3 minutes sit-to-stand test, 1 minute sit-to-stand test, 6 minutes walk test will be performed 2 times for each patients 3 minutes sit-to-stand test with oxygen uptake measurement will be performed one time for each patient
Sponsors
University Hospital, Grenoble
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Intervention model description
The investigators want to test the reproductibility of a 3 minutes sit-to-stand test in patients with idiopathic pulmonary fibrosis. For this, patient perform the test during 2 visits and the investigators are going to compare the results of the two visits.
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* man or woman aged less than 85 years * patients with Idiopathic Pulmonary Fibrosis without any acute exacerbation during 4 months before the inclusion * Non-opposition to participation in research * Patient with 6 minutes walk test \> 200 meters (with or without oxygen therapy)
Exclusion criteria
* Patient with reduced locomotor activity, or joint pain that compromises the performance of the tests * Patient with 6 minutes walk test \< 200 meters * Patient with an other etiology of pulmonary fibrosis * Other significant pulmonary diseases * Patient with unstable cardiac disease * Patient who may be, according to the investigator's assessment, not cooperating or respecting the obligations inherent in participating to the study. * Opposition to participation in research
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reproductibility of the 3 minutes sit-to-stand test in patient with idiopathic pulmonary fibrosis | 2 days | Evaluate the reproductibility for the number of rise and down during the 3 minutes sit-to-stand test of the 2 visits (the investigators will compare the number of rise and sit during the 3 minutes sit-to-stand test of the 2 visits to see if they are similar) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 3 minutes sit-to-stand test compared to the 6 minutes walk test: oxygen saturation | 2 days | compared oxygen saturation during the 3 minutes sit-to-stand test to the 6 minutes walk test |
| 1 minute sit-to-stand test compared to 3 minutes sit-to-stand: oxygen saturation | 2 days | Compared oxygen saturation during the 3 minutes sit-to-stand test with 1 minute sit-to-stand test |
| Functional response during the 3 minutes sit-to-stand test: Heart rate | 2 days | Evaluate the reproductibility of functional response (heart rate) during the 3 minutes sit-to-stand test |
| Functional response during the 3 minutes sit-to-stand test: symptoms | 2 days | Evaluate the reproductibility of functional response (symptoms) during the 3 minutes sit-to-stand test |
| Functional response during the 3 minutes sit-to-stand test: Oxygen saturation | 2 days | Evaluate the reproductibility of functional response (oxygen saturation) during the 3 minutes sit-to-stand test |
| 3 minutes sit-to-stand test compared to the 6 minutes walk test: symptoms | 2 days | Compared symptoms during the 3 minutes sit-to-stand test to the 6 minutes walk test |
| 1 minute sit-to-stand test compared to 3 minutes sit-to-stand: heart rate | 2 days | Compared heart rate during the 3 minutes sit-to-stand test with 1 minute sit-to-stand test |
| 1 minute sit-to-stand test compared to 3 minutes sit-to-stand: symptoms | 2 days | Compared symptoms during the 3 minutes sit-to-stand test with 1 minute sit-to-stand test |
| 3 minutes sit-to-stand test compared to the 6 minutes walk test: heart rate | 2 days | Compared heart rate during the 3 minutes sit-to-stand test to the 6 minutes walk test |
Countries
France
Outcome results
None listed