Lamina Cribrosa Depth Change With Change in Eye Pressure

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03267849

Enrollment

309

Registered

2017-08-30

Start date

2017-07-01

Completion date

2024-10-10

Last updated

2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma, Open-Angle

Keywords

biomarker

Brief summary

This is a study of the compliance of the lamina cribrosa with change in eye pressure.

Detailed description

Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by one of two interventions, wearing goggles or having laser suturelysis

Interventions

OTHERwearing swimming goggles or having laser suturelysis

Two images will be compared in each subject at two different eye pressures with the higher pressure having been produced by the interventions

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to 100 Years

Healthy volunteers

Yes

Inclusion criteria

* persons who consent to drink water and be imaged

Exclusion criteria

* non-consenting persons * those who cannot be imaged

Design outcomes

Primary

Measure	Time frame	Description
Change in anterior lamina cribrosa depth	Up to 2 months	OCT position of lamina measured at 2 eye pressures. Data will be calculated as change in parameters of interest per mm Hg change in eye pressure

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026