Hyperbilirubinemia, Neonatal
Conditions
Brief summary
Neonatal Jaundice occurs in 60% of term infants and 80% of premature infants. Although it is transient, it is associated with high rate of readmission of patients in the first week of infancy. Neonatal jaundice can cause neurological complications and kernicterus. Considering the fact that there have been a lot of studies on probiotic role in management of necrotizing enterocolitis (NEC) and few studies on their role in neonatal jaundice, we carried out this study to determine the efficacy and safety of probiotics in neonatal hyperbilirubinemia in infants hospitalized in children hospital in Bandar Abbas.
Interventions
DRUGProbiotic
Probiotics drop
Sponsors
Hormozgan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
2 Days to 28 Days
Healthy volunteers
No
Inclusion criteria
* Between 2 and 28 days old * Having jaundice * Gestational age between 35-42 weeks
Exclusion criteria
* Less than 2 days or more than 28 days old * Gestational age out of the range of 35-42 weeks * Infants whose parents refused to cooperate * Patients with sepsis and other comorbid conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of phototherapy | 6 days | Duration of phototherapy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Discharge rate | 6 days | percentage of infants discharged from the hospital at 2nd, 3rd, 4th, and 5th days of admission |
Countries
Iran
Contacts
Primary ContactRakhshaneh Goodarzi, M.D
Outcome results
None listed