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The Endothelial Count in Pxf

The Corneal Endothelial Cell Count in Eyes With Pseudoexfoliation Syndrome

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03265457
Enrollment
20
Registered
2017-08-29
Start date
2018-10-01
Completion date
2020-10-01
Last updated
2018-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pseudoexfoliation Syndrome

Brief summary

Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.

Detailed description

The corneal Endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency. In patients with pseudoexfoliation syndrome , quantitative and qualitative morphological changes of the corneal endothelium have been demonstrated in specular and electron microscopic studies. Specular microscopy is a non-invasive technique to access the structure and function of the corneal endothelium. Our research question is to study Endothelial cell count in patients with pseudoexfoliation syndrome & compare it to age matched group.

Interventions

Comparison between corneal Endothelial count in patients with pseudoexfoliation syndrome and age matched group

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Patients with pseudoexfoliation syndrome

Exclusion criteria

* Patients with previous intra ocular surgeries. * Patients with uveitis * Patients with fuck's endothelial dystrophy

Design outcomes

Primary

MeasureTime frameDescription
Comparison between endothelial cell count in patients with Pseudoexfoliation syndrome and age matched controls.One yearThe corneal Endothelial cell count in patients with pseudoexfoliation syndrome will be measured by the specular microscopy & compared with the normal endothelial count in people at the same group

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026