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A Single-patient Study of Repeat-dose Administration of Prometic Plasminogen (Human) Intravenous

A Single-patient Study of Repeat-dose Administration of ProMetic Plasminogen (Human) Intravenous Infusion in an Adult With Hypoplasminogenemia

Status
NO_LONGER_AVAILABLE
Phases
Unknown
Study type
Expanded Access
Source
ClinicalTrials.gov
Registry ID
NCT03265171
Enrollment
Unknown
Registered
2017-08-29
Start date
Unknown
Completion date
Unknown
Last updated
2020-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoplasminogenemia

Brief summary

These are single-patient studies with repeat-dose administration of ProMetic Plasminogen IV infusion in one adult and one child with hypoplasminogenemia. These patients are under treatment to address wound healing and obstructions.

Interventions

BIOLOGICALPlasminogen (Human)

Sponsors

Cedars-Sinai Medical Center
CollaboratorOTHER
Vanderbilt University Medical Center
CollaboratorOTHER
Indiana Hemophilia &Thrombosis Center, Inc.
CollaboratorOTHER
Prometic Biotherapeutics, Inc.
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
ALL
Age
16 Months to No maximum

Inclusion criteria

* Patient has provided informed consent. * Patient has a diagnosis of compound homozygous Type 1 plasminogen deficiency as evidence by ligneous conjunctivitis since birth as well as involvement of the conjunctiva, nasopharynx, gingiva, tracheobronchial tree, gastrointestinal tract, and urinary tract.

Exclusion criteria

* Not applicable

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026